Clinical tools

Liver Health Calculators

Free, private calculators that help you understand common clinical measurements. Estimate APRI and FIB-4 liver fibrosis screening scores, check your triglyceride to HDL ratio, or calculate adult BMI.

Liver fibrosis assessment

APRI Calculator

Estimate the AST to Platelet Ratio Index using values from a blood test report.

Formula

APRI = (AST ÷ AST upper limit ÷ platelet count) × 100

Your APRI score

Enter all three values to see the result.

Your values are calculated in this browser and are not sent to a server.

APRI score interpretation

APRI scoreInterpretationLikelihood of liver fibrosis
< 0.5Minimal or no fibrosisLow
0.5–1.5Moderate fibrosis or significant fibrosisIntermediate
> 1.5Severe fibrosis or cirrhosisHigh
Important: APRI is a screening estimate, not a diagnosis. Results are best interpreted by a qualified clinician alongside medical history, examination, imaging, and other tests. Published thresholds are primarily based on studies of people with hepatitis C.

Formula and clinical background reference: Hepatitis C Online, University of Washington. Source evidence includes Lin et al., Hepatology (2011), and Chou & Wasson, Annals of Internal Medicine (2013).

What is an APRI calculator?

APRI stands for AST to Platelet Ratio Index. It is a non-invasive calculation that combines an aspartate aminotransferase blood test result with platelet count. Clinicians may use APRI as one part of liver fibrosis assessment, especially in people with hepatitis C. It can help estimate risk, but it does not replace clinical evaluation, imaging, elastography, or other fibrosis tests.

How to use the APRI calculator

  1. 1. Enter AST: use the AST level shown on the blood test report in IU/L.
  2. 2. Enter the laboratory upper limit: use the AST upper limit of normal from the same report. If unavailable, 40 IU/L is commonly used in APRI studies.
  3. 3. Enter platelet count: use the result expressed in 10⁹/L.

Advanced fibrosis screening

FIB-4 Calculator

Estimate the Fibrosis-4 score using age and routine blood test results.

Formula

FIB-4 = (age × AST) ÷ (platelet count × √ALT)

Your FIB-4 score

Enter all four values to see the result.

Your values are calculated in this browser and are not sent to a server.

FIB-4 interpretation for advanced fibrosis

Below 1.45

Advanced fibrosis less likely

1.45–3.25

Indeterminate result

Above 3.25

Advanced fibrosis more likely

Important: FIB-4 is a screening estimate, not a diagnosis. The original thresholds were validated in adults with HIV/HCV coinfection, and performance can differ by age, condition, and population. A clinician should interpret the result with medical history and other fibrosis assessments.

Formula, thresholds, and clinical background reference: Hepatitis C Online, University of Washington. Original validation: Sterling et al., Hepatology (2006).

What is a FIB-4 calculator?

The Fibrosis-4 score combines age, AST, ALT, and platelet count to estimate the likelihood of advanced liver fibrosis. It is a non-invasive screening calculation that can help clinicians decide whether additional fibrosis assessment may be appropriate.

How to use the FIB-4 calculator

  1. 1. Enter age: use the patient’s age in years.
  2. 2. Enter AST and ALT: use results from the same blood test in U/L.
  3. 3. Enter platelet count: use the result expressed in 10⁹/L.

Metabolic health screening

Triglyceride to HDL Ratio Calculator

Calculate the triglyceride to HDL cholesterol ratio from a standard lipid profile.

Formula

TG/HDL ratio = triglycerides ÷ HDL cholesterol

Your TG/HDL ratio

Enter both values to see the result.

Your values are calculated in this browser and are not sent to a server.

TG/HDL ratio ranges (mg/dL)

Below 2.0

Lower ratio

2.0–3.9

Intermediate ratio

4.0 or above

Higher ratio

If your report uses mmol/L, select mmol/L above. The calculator converts the values to mg/dL (triglycerides × 88.57, HDL × 38.67), so the same ranges apply. A ratio of 2.0 in mg/dL is about 0.87 in mmol/L.

Important: The TG/HDL ratio is a screening marker, not a diagnosis. There is no single guideline cutoff, and suitable thresholds differ by sex, ethnicity, and population. Triglycerides are best measured after fasting. A clinician should interpret the result with the full lipid profile, blood sugar tests, liver health, and medical history.

Clinical background: McLaughlin et al., Annals of Internal Medicine (2003), which used a TG/HDL ratio of 3.0 or above to identify insulin resistance in overweight adults.

What is the triglyceride to HDL ratio?

The triglyceride to HDL ratio divides your triglyceride level by your HDL (good) cholesterol level. A higher ratio has been linked with insulin resistance, small dense LDL particles, and fatty liver disease. It is a simple marker that can be calculated from a routine lipid profile.

How to use the TG/HDL ratio calculator

  1. 1. Choose units: select mg/dL or mmol/L to match your lab report.
  2. 2. Enter triglycerides: use a fasting result if available.
  3. 3. Enter HDL cholesterol: use the result from the same lipid profile.

Healthy weight screening

BMI Calculator

Calculate adult body mass index using metric or imperial measurements.

Your BMI

Enter your weight and height to see the result.

Your measurements stay on your device and are not stored or transmitted.

Adult BMI ranges

Below 18.5

Underweight

18.5–24.9

Healthy weight

25.0–29.9

Overweight

30.0 or above

Obesity range

BMI is a screening measure for adults, not a direct measurement of body fat or overall health. It may be less informative for children, pregnancy, older adults, and people with high muscle mass. Discuss weight or health concerns with a qualified clinician.

How the BMI calculator works

Body mass index compares weight with height to provide a general adult weight category. The metric formula is weight in kilograms divided by height in metres squared. The imperial formula multiplies weight in pounds by 703, then divides by height in inches squared.

BMI can be useful for population screening, but it does not measure body fat distribution, muscle mass, nutrition, or metabolic health. Waist measurement, medical history, laboratory results, and a clinician’s assessment can provide a more complete health picture.

Frequently asked questions

What is the APRI score?

The AST to Platelet Ratio Index is a non-invasive estimate that uses AST, the AST upper limit of normal, and platelet count to help assess the likelihood of liver fibrosis or cirrhosis.

How is APRI calculated?

Divide AST by the AST upper limit of normal, divide that result by platelet count in 10⁹/L, and multiply by 100.

How is FIB-4 calculated?

Multiply age by AST, then divide by platelet count multiplied by the square root of ALT. Scores below 1.45 and above 3.25 were used as lower and upper cutoffs in the original validation study.

What is a good triglyceride to HDL ratio?

Using mg/dL values, a ratio below 2.0 is generally considered favourable. Ratios of about 3.0 and above have been linked with insulin resistance, and 4.0 or above with higher cardiometabolic risk.

What is a healthy BMI for adults?

For most adults, a BMI from 18.5 to 24.9 is generally classified as a healthy weight range. BMI is a screening measure, not a diagnosis.

Are my calculator values stored?

No. APRI, FIB-4, TG/HDL, and BMI calculations happen in your browser. The values you enter are not submitted to or stored on a server.